CRISPR-mediated multigene integration enables Shikimate pathway refactoring for enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus
Mengwan Li, Xuye Lang, Marcos Moran Cabrera, Sawyer De Keyser, Xiyan Sun, Nancy Da Silva +1 more
Biotechnology for Biofuels
Abstract
The CRISPR-mediated multigene integration system expands the genome-editing toolset for K. marxianus, a promising multi-stress tolerant host for the biosynthesis of 2-PE and other aromatic compounds derived from the Shikimate pathway.
Extracted Claims
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technique_parameter100% confidence
CRISPR-mediated multigene integration system enables enhanced 2-phenylethanol biosynthesis in Kluyveromyces marxianus
“The CRISPR-mediated multigene integration system expands the genome-editing toolset for K. marxianus, a promising multi-stress tolerant host for the biosynthesis of 2-PE and other aromatic compounds d...”
Concepts
Kluyveromyces marxianusShikimate pathwayMetabolic engineeringBiologyCRISPRGeneSynthetic biologyBiochemistry