2021peer-reviewed93 citations
Urolithin A ameliorates experimental autoimmune encephalomyelitis by targeting aryl hydrocarbon receptor
Pei-Xin Shen, Xing Li, Si-Ying Deng, Li Zhao, Yanyan Zhang, Xin Deng +5 more
EBioMedicine
Abstract
Collectively, our study offers new evidence that URA, as a human microbial metabolite, is valuable to use as a prospective therapeutic candidate for autoimmune diseases.
Concepts
Experimental autoimmune encephalomyelitisAryl hydrocarbon receptorMicrogliaEncephalomyelitisImmunologyBiologyReceptorIn vivo