The Wonderful Activities of the Genus Mentha: Not Only Antioxidant Properties
Majid Tafrihi, Muhammad Imran, Tabussam Tufail, Tanweer Aslam Gondal, Gianluca Caruso, Somesh Sharma +5 more
Molecules
Abstract
Medicinal plants and their derived compounds have drawn the attention of researchers due to their considerable impact on human health. Among medicinal plants, mint (<i>Mentha</i> species) exhibits multiple health beneficial properties, such as prevention from cancer development and anti-obesity, antimicrobial, anti-inflammatory, anti-diabetic, and cardioprotective effects, as a result of its antioxidant potential, combined with low toxicity and high efficacy. <i>Mentha</i> species are widely used in savory dishes, food, beverages, and confectionary products. Phytochemicals derived from mint also showed anticancer activity against different types of human cancers such as cervix, lung, breast and many others. Mint essential oils show a great cytotoxicity potential, by modulating MAPK and PI3k/Akt pathways; they also induce apoptosis, suppress invasion and migration potential of cancer cells lines along with cell cycle arrest, upregulation of Bax and p53 genes, modulation of TNF, IL-6, IFN-γ, IL-8, and induction of senescence phenotype. Essential oils from mint have also been found to exert antibacterial activities against <i>Bacillus subtilis</i>, <i>Streptococcus aureus</i>, <i>Pseudomonas aeruginosa</i>, and many others. The current review highlights the antimicrobial role of mint-derived compounds and essential oils with a special emphasis on anticancer activities, clinical data and adverse effects displayed by such versatile plants.
Extracted Claims
9 claims extracted from this paper into the knowledge graph
Mint essential oils exhibit antibacterial activities against Bacillus subtilis, Streptococcus aureus, Pseudomonas aeruginosa, and many others
“Essential oils from mint have also been found to exert antibacterial activities against Bacillus subtilis, Streptococcus aureus, Pseudomonas aeruginosa, and many others.”
Mint essential oils induce senescence phenotype in cancer cells
“Mint essential oils show a great cytotoxicity potential, by modulating MAPK and PI3k/Akt pathways; they also induce apoptosis, suppress invasion and migration potential of cancer cells lines along wit...”
Mint essential oils show cytotoxicity potential by modulating MAPK and PI3k/Akt pathways
“Mint essential oils show a great cytotoxicity potential, by modulating MAPK and PI3k/Akt pathways; they also induce apoptosis, suppress invasion and migration potential of cancer cells lines along wit...”