The Importance of Maintaining a Low Omega-6/Omega-3 Ratio for Reducing the Risk of Autoimmune Diseases, Asthma, and Allergies.
James J. DiNicolantonio, James H. O’Keefe
PubMed
Abstract
Up until about 100 years ago, the omega-6/3 ratio has been around 4:1 or less. However, the typical Western diet now provides an omega-6/3 ratio of approximately 20:1 in favor of omega-6. This predisposes to supraphysiologic inflammatory responses and perpetuates chronic low-grade inflammation. The overconsumption of linoleic acid, mainly from industrial omega-6 seed oils, and the lack of long-chain omega-3s in the diet creates a pro-inflammatory, pro-allergic, pro-thrombotic state. Reducing the omega-6/3 ratio, particularly through reductions in the intake of refined omega-6 seed oil, and increasing the intake of marine omega-3s, either through dietary means or supplementation, may be an effective strategy for reducing inflammation, allergies, and autoimmune reactions.
Extracted Claims
4 claims extracted from this paper into the knowledge graph
omega-6/3 ratio predisposes to supraphysiologic inflammatory responses
“This predisposes to supraphysiologic inflammatory responses and perpetuates chronic low-grade inflammation.”
long-chain omega-3s reduces inflammation, allergies, and autoimmune reactions
“Reducing the omega-6/3 ratio, particularly through reductions in the intake of refined omega-6 seed oil, and increasing the intake of marine omega-3s, either through dietary means or supplementation, ...”
omega-6/3 ratio predisposes to chronic low-grade inflammation
“This predisposes to supraphysiologic inflammatory responses and perpetuates chronic low-grade inflammation.”