2022peer-reviewed42 citations
Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer
Muhammad Furqan, Taher Abu Hejleh, Laura Stephens, Stacey M. Hartwig, Sarah L. Mott, Casey Pulliam +21 more
Redox Biology
Abstract
The addition of P-AscH- to platinum-based chemotherapy improved tumor response in advanced stage NSCLC. P-AscH- appears to alter the host immune response and needs further investigation as a potential adjuvant to immunotherapy.
Concepts
MedicineCarboplatinInternal medicineChemotherapyOncologyLung cancerResponse Evaluation Criteria in Solid TumorsClinical endpoint