Human Breast Milk: From Food to Active Immune Response With Disease Protection in Infants and Mothers
Adjimon Gatien Lokossou, Léonce Kouakanou, Anne Schumacher, Ana Claudia Zenclussen
Frontiers in Immunology
Abstract
Breastfeeding is associated with long-term wellbeing including low risks of infectious diseases and non-communicable diseases such as asthma, cancer, autoimmune diseases and obesity during childhood. In recent years, important advances have been made in understanding the human breast milk (HBM) composition. Breast milk components such as, non-immune and immune cells and bioactive molecules, namely, cytokines/chemokines, lipids, hormones, and enzymes reportedly play many roles in breastfed newborns and in mothers, by diseases protection and shaping the immune system of the newborn. Bioactive components in HBM are also involved in tolerance and appropriate inflammatory response of breastfed infants if necessary. This review summarizes the current literature on the relationship between mother and her infant through breast milk with regard to disease protection. We will shed some light on the mechanisms underlying the roles of breast milk components in the maintenance of health of both child and mother.
Extracted Claims
3 claims extracted from this paper into the knowledge graph
human breast milk involves tolerance and appropriate inflammatory response of breastfed infants
“Bioactive components in HBM are also involved in tolerance and appropriate inflammatory response of breastfed infants if necessary.”
human breast milk contains non-immune and immune cells and bioactive molecules
“Breast milk components such as, non-immune and immune cells and bioactive molecules, namely, cytokines/chemokines, lipids, hormones, and enzymes reportedly play many roles in breastfed newborns and in...”
human breast milk plays roles in disease protection and shaping the immune system of the newborn
“Breast milk components such as, non-immune and immune cells and bioactive molecules, namely, cytokines/chemokines, lipids, hormones, and enzymes reportedly play many roles in breastfed newborns and in...”