Traditional Chinese medicine active ingredients-based selenium nanoparticles regulate antioxidant selenoproteins for spinal cord injury treatment
Siyuan Rao, Yongpeng Lin, Rui Lin, Jinggong Liu, Hongshen Wang, Wei-Xiong Hu +2 more
Journal of Nanobiotechnology
Abstract
TSIIA@SeNPs-APS exhibited promising therapeutic effects in the anti-oxidation therapy of SCI, which paved the way for developing the synergistic effect of TCM active ingredients by nanotechnology to improve the efficacy as well as establishing novel treatments for oxidative stress-related diseases associated with Se metabolism and selenoproteins regulation.
Concepts
AntioxidantPharmacologyIn vivoChemistryOxidative stressApoptosisBioavailabilityNeuroprotection