2022peer-reviewed92 citations
Urolithin B suppressed osteoclast activation and reduced bone loss of osteoporosis via inhibiting <scp>ERK</scp>/<scp>NF‐κB</scp> pathway
Yajun Li, Qi Zhuang, Lihong Tao, Kai Zheng, Shuangshuang Chen, Yunshang Yang +10 more
Cell Proliferation
Abstract
Urolithin B attenuated bone loss in OVX mice by inhibiting the formation and activation of osteoclasts via down-regulation of the ERK/NF-κB signalling pathway.
Concepts
OsteoclastMAPK/ERK pathwayRANKLOvariectomized ratWestern blotChemistryBone resorptionBone marrow