Encapsulation of Mesona chinensis Benth Extract in Alginate Beads Enhances the Stability and Antioxidant Activity of Polyphenols under Simulated Gastrointestinal Digestion
Chonnipa Wongverawattanakul, Phim on Suklaew, Charoonsri Chusak, Sirichai Adisakwattana, Thavaree Thilavech
Foods
Abstract
The aim of this study was to investigate the stability and antioxidant activity of the polyphenols from <i>Mesona chinensis</i> Benth extract (MCE) and its alginate-based encapsulation by extrusion technique during simulated gastrointestinal digestion. The encapsulation efficacy ranged from 41.1 ± 4.7 to 56.7 ± 3.4% with different concentrations of MCE (50-75% <i>v</i>/<i>v</i>), sodium alginate (1.2-1.8% <i>w</i>/<i>v</i>), and CaCl<sub>2</sub> solution (3-5% <i>w</i>/<i>v</i>). The optimal condition for MCE-loaded alginate beads (MCB) was composed of 75% MCE, 1.5% alginate, and 3% CaCl<sub>2</sub> solution, which provided the highest encapsulation efficiency with a spherical structure and a mean particle diameter of 1516.67 ± 40.96 μm. Fourier transform infrared spectroscopy (FT-IR) reported no chemical interaction between alginate and MCE. The release of total phenolic content (TPC) was only 8.9% after placing MCB in water for 4 h. After simulated digestion, changes in TPC and ferric reducing antioxidant power (FRAP) of MCE significantly decreased by 25.0% and 29.7%, respectively. Interestingly, the incorporation of MCB significantly increased TPC and FRAP in the digesta compared to those of MCE during gastrointestinal tract conditions. The findings suggest that the encapsulation of MCE with alginate as a carrier helps to improve the bioaccessibility and biological activity of <i>M. chinensis</i> polyphenols.
Extracted Claims
7 claims extracted from this paper into the knowledge graph
encapsulation enhances stability and antioxidant activity of polyphenols
“The aim of this study was to investigate the stability and antioxidant activity of the polyphenols from <i>Mesona chinensis</i> Benth extract (MCE) and its alginate-based encapsulation by extrusion te...”
incorporation of MCB increases TPC and FRAP in the digesta
“Interestingly, the incorporation of MCB significantly increased TPC and FRAP in the digesta compared to those of MCE during gastrointestinal tract conditions.”
encapsulation increases bioaccessibility and biological activity of <i>M. chinensis</i> polyphenols
“The findings suggest that the encapsulation of MCE with alginate as a carrier helps to improve the bioaccessibility and biological activity of <i>M. chinensis</i> polyphenols.”