The bioactivities of sclareol: A mini review
Jianbo Zhou, Xiaofang Xie, Hailin Tang, Cheng Peng, Peng Fu
Frontiers in Pharmacology
Abstract
Sclareol, a diterpene alcohol isolated from the herbal and flavor plant clary sage (Salvia sclarea L.), is far-famed as the predominant ingredient in the refined oil of Salvia sclarea (L.). The empirical medicine of <i>Salvia sclarea</i> L. focused on various diseases, such as arthritis, oral inflammation, digestive system diseases, whereas the sclareol possessed more extensive and characteristic bioactivities, including anti-tumor, anti-inflammation and anti-pathogenic microbes, even anti-diabetes and hypertension. However, there is a deficiency of literature to integrate and illuminate the pharmacological attributes of sclareol based on well-documented investigations. Interestingly, sclareol has been recently considered as the potential candidate against COVID-19 and Parkinson's disease. Accordingly, the bioactive attributes of sclareol in cancer, inflammation, even pharmacochemistry and delivery systems are reviewed for comprehensively dissecting its potential application in medicine.
Extracted Claims
2 claims extracted from this paper into the knowledge graph
sclareol is considered a potential candidate against COVID-19 and Parkinson's disease
“Interestingly, sclareol has been recently considered as the potential candidate against COVID-19 and Parkinson's disease.”
sclareol possesses anti-tumor, anti-inflammation, anti-pathogenic microbes, anti-diabetes, and anti-hypertension properties
“the sclareol possessed more extensive and characteristic bioactivities, including anti-tumor, anti-inflammation and anti-pathogenic microbes, even anti-diabetes and hypertension.”