Combination therapy: synergism among three plant extracts against selected pathogens
Martin Ntiamoah Donkor, Addai-Mensah Donkor, Richard Mosobil
BMC Research Notes
Abstract
Compared with the data of the individual extracts, the MIC values of the extract-extract combinations against all strains of the tested microorganisms were significantly lower, ranging from 0.97 to 1.17, 0.97 to 4.69, 0.50 to 1.17, 1.17 to 3.12 and 2.34 to 4.69 mg/mL for Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumonia and Candida albicans respectively. L. bateri aqueous-S. alata ethanol extracts and S. alata aqueous-R. cummunis ethanol extracts combinations showed a synergy effect against all the test microorganisms. The other combinations exhibited at least one additive effect. Neither antagonism nor indifference activity was observed. This study validates the relevance of combining these plants in treating infections by traditional medicine practitioners.
Extracted Claims
4 claims extracted from this paper into the knowledge graph
Combination of L. bateri aqueous-S. alata ethanol extracts shows synergy effect against all test microorganisms
“L. bateri aqueous-S. alata ethanol extracts and S. alata aqueous-R. cummunis ethanol extracts combinations showed a synergy effect against all the test microorganisms.”
Combination of S. alata aqueous-R. cummunis ethanol extracts shows synergy effect against all test microorganisms
“L. bateri aqueous-S. alata ethanol extracts and S. alata aqueous-R. cummunis ethanol extracts combinations showed a synergy effect against all the test microorganisms.”
Other combinations of plant extracts exhibit at least one additive effect
“The other combinations exhibited at least one additive effect.”