Potential Clinical Applications of Pro-Resolving Lipids Mediators from Docosahexaenoic Acid
María Paz Beyer, Luis A. Videla, Camila Farías, Rodrigo Valenzuela
Nutrients
Abstract
Docosahexaenoic acid (C22:6<i>n</i>-3, DHA) is the precursor of specialized pro-resolving lipid mediators (SPMs), such as resolvin, protectin, and maresin families which have been considered therapeutic bioactive compounds for human health. Growing evidence indicates that DHA and SPMs are beneficial strategies in the amelioration, regulation, and duration of inflammatory processes through different biological actions. The present review discusses the reported therapeutic benefits of SPMs on various diseases and their potential clinical applications.
Extracted Claims
2 claims extracted from this paper into the knowledge graph
Docosahexaenoic acid (DHA) is a precursor of specialized pro-resolving lipid mediators (SPMs)
“Docosahexaenoic acid (C22:6<i>n</i>-3, DHA) is the precursor of specialized pro-resolving lipid mediators (SPMs), such as resolvin, protectin, and maresin families”
SPMs have therapeutic benefits various diseases
“The present review discusses the reported therapeutic benefits of SPMs on various diseases and their potential clinical applications.”