Probiotics, Prebiotics, Lactoferrin, and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants
Yuting Wang, Iván D. Flórez, Rebecca L. Morgan, Farid Foroutan, Yaping Chang, Holly N. Crandon +12 more
JAMA Pediatrics
Abstract
In this systematic review and NMA, moderate- to high-certainty evidence demonstrated an association between multistrain probiotics and reduction in all-cause mortality; these interventions were also associated with the best effectiveness for other key outcomes. Combination products, including single- and multiple-strain probiotics combined with prebiotics or lactoferrin, were associated with the largest reduction in morbidity and mortality.
Extracted Claims
2 claims extracted from this paper into the knowledge graph
multistrain probiotics reduce all-cause mortality
“In this systematic review and NMA, moderate- to high-certainty evidence demonstrated an association between multistrain probiotics and reduction in all-cause mortality; these interventions were also a...”
combination products reduce morbidity and mortality
“Combination products, including single- and multiple-strain probiotics combined with prebiotics or lactoferrin, were associated with the largest reduction in morbidity and mortality.”