1987peer-reviewed3,300 citations
INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS
Michael J. Berridge
Annual Review of Biochemistry
Abstract
The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More
Concepts
Second messenger systemDrosophila melanogasterDiacylglycerol kinaseCell biologyRegulatorInositolBiologySignal transduction