1995Scientific literature3,423 citations Open Access

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Dario R. Alessi, Ana Cuenda, Philip Cohen +2

Journal of Biological Chemistry

Kinase

PD 098059 has been shown previously to inhibit the dephosphorylated form of mitogen-activated protein kinase kinase-1 (MAPKK1) and a mutant MAPKK1(S217E,S221E), which has low levels of constitutive...

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1980Scientific literature3,421 citationsDOI

Herbivory in Relation to Plant Nitrogen Content

William J. Mattson

Annual Review of Ecology and Systematics

Research Library

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

Herbivory in Relation to Plant Nitrogen Content

The Impact of Corporate Sustainability on Organizational Processes and Performance

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

Ab initio study of solvated molecules: a new implementation of the polarizable continuum model

Correlation of separation factor versus permeability for polymeric membranes

Strategic alliances and interfirm knowledge transfer

Silk-based biomaterials

Graphene, related two-dimensional crystals, and hybrid systems for energy conversion and storage

States of Injury

SUPEROXIDE RADICAL AND SUPEROXIDE DISMUTASES

The Statistical Analysis of Compositional Data

Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors

Clinical Practice Guideline for the Use of Antimicrobial Agents in Neutropenic Patients with Cancer: 2010 Update by the Infectious Diseases Society of America

Synthesis and Activity of a New Generation of Ruthenium-Based Olefin Metathesis Catalysts Coordinated with 1,3-Dimesityl-4,5-dihydroimidazol-2-ylidene Ligands

Social dominance: an intergroup theory of social hierarchy and oppression

Effects of particle size, particle/matrix interface adhesion and particle loading on mechanical properties of particulate–polymer composites

Monodisperse MFe<sub>2</sub>O<sub>4</sub> (M = Fe, Co, Mn) Nanoparticles

A dimer method for finding saddle points on high dimensional potential surfaces using only first derivatives

Within-group agreement, non-independence, and reliability: Implications for data aggregation and analysis.

High-power all-solid-state batteries using sulfide superionic conductors

Special report on emissions scenarios

Fundamental principles and applications of natural gas hydrates

Nitric oxide and the immune response

Hypoxia-Inducible Factors in Physiology and Medicine

Contemporary Definitions and Classification of the Cardiomyopathies

Types of gas fluidization

Virus interference. I. The interferon

Selenium and human health

Electrochemical Glucose Biosensors

New Fe-based soft magnetic alloys composed of ultrafine grain structure

The Anatomy and Taxonomy of Protein Structure

A New Quick-Response and High-Efficiency Control Strategy of an Induction Motor

Earth-abundant catalysts for electrochemical and photoelectrochemical water splitting

The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation

Silica-Like Malleable Materials from Permanent Organic Networks

Fourier Transform Infrared Spectroscopic Analysis of Protein Secondary Structures

Gold Catalysis

Knowledge and Organization: A Social-Practice Perspective

Absolute electronegativity and hardness: application to inorganic chemistry

Frontier Orbitals and Organic Chemical Reactions

A "DIRECT-COLORING" THIOCHOLINE METHOD FOR CHOLINESTERASES

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

Sufficient Sample Sizes for Multilevel Modeling

Sequences of proteins of immunological interest

The Isoelectric Points of Solid Oxides, Solid Hydroxides, and Aqueous Hydroxo Complex Systems

Low-cost adsorbents for heavy metals uptake from contaminated water: a review

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

Occurrence of drugs in German sewage treatment plants and rivers