2022Academic literature4,426 citations Open Access

Copper induces cell death by targeting lipoylated TCA cycle proteins

Peter Tsvetkov, Shannon Coy, Boryana Petrova +15

Science

Trace Elements in Health

Copper is an essential cofactor for all organisms, and yet it becomes toxic if concentrations exceed a threshold maintained by evolutionarily conserved homeostatic mechanisms. How excess copper...

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2021Scientific literature3,540 citations Open Access

Lipid nanoparticles for mRNA delivery

Xucheng Hou, Tal Zaks, Róbert Langer +1

Research Library

Copper induces cell death by targeting lipoylated TCA cycle proteins

Lipid nanoparticles for mRNA delivery

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